![]() These are directly or indirectly related to the GIS problems seen in old age. With aging, many physiologic changes occur in the gastrointestinal system (GIS), such as a decrease in the stomach's elasticity, gastric secretions, and mobility gastric atrophy and delayed gastric emptying ( 5). On the other hand, reflux oesophagitis is more severe in the elderly than in adult or young subjects ( 4). Gastro-esophageal reflux disease is most common (25%) among individuals aged 25–35 years and prevalence in the elderly is 14–20% ( 3). A defective antireflux barrier, abnormal esophageal clearance, reduced salivary production, altered esophageal mucosal resistance, and delayed gastric emptying can be mentioned among the pathogenic abnormalities causing GERD ( 2). ![]() Gastro-esophageal reflux disease is defined as the gastric contents' abnormal reflux into the esophagus, resulting in mucosal damage. However, when reflux recurs at frequent intervals during the day, occurs over longer periods, and especially occurs during sleep, it is known as gastro-esophageal reflux disease (GERD). Physiologic reflux may be imperceptible or produce very mild symptoms due to its short duration. Reflux is the retrograde movement of stomach contents toward the distal esophagus, which can normally be observed approximately 10–15 times a day and accepted as physiological ( 1). Older patients had more important endoscopic findings such as hernia, esophagitis, and cancer. However, significantly more serious endoscopic findings were noted in the older patients compared with the younger patients.Ĭonclusion: The older and young patients with GERD were predominantly male and typical reflux problems were less common in older patients with GERD. The older patients had less severe and rare typical symptoms than the young patients. The male/female ratio was 5/3 and 2/1 in the young and older groups, respectively. The mean age of the older group was 68.2 ± 4.5 years and the mean age of the young group was 38 ± 7.2 years. Results: Two hundred eighty-six patients aged over 65 years and 261 patients aged below 50 years were enrolled in this study. The SPSS 11.0 for Windows pocket program was used for statistical analysis. The diagnosis of GERD was made according to the patients' symptoms. The exclusion criteria included prior surgery, age under 18 years, and pregnancy. The criteria for inclusion were being aged over 65 and under 50 years and having an upper gastrointestinal endoscopy with reflux symptoms resistant to ppi theraphy. Materials and Methods: The clinical and endoscopic features were evaluated for all patients with GERD between January 2017 and September 2020. Objective: To determine and compare the clinical features and endoscopic findings of gastro-esophageal reflux disease (GERD) in elderly and younger age groups.
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